Understanding selective trafficking of lymphocyte subsets
نویسندگان
چکیده
منابع مشابه
Understanding selective trafficking of lymphocyte subsets.
Chemokine receptor expression is finely controlled during T-cell development. We show that newly identified chemokine receptor Bonzo/CXCR6 is expressed by subsets of Th1 or T-cytotoxic 1 (Tc1) cells, but not by Th2 or Tc2 cells, establishing Bonzo as a differential marker of polarized type 1 T cells in vitro and in vivo. Priming of naive T cells by dendritic cells induces expression of Bonzo on...
متن کاملCD8+ T Lymphocyte Subsets in Bladder Tumor Draining Lymph Nodes
Background: Cytotoxic CD8+ T cells, as essential parts of the adaptive immune system, play pivotal roles in anti-tumor immune responses. It is well documented that cytokine expression profiles and activation status of these cells during anti-tumor immune responses affect the outcome of host-tumor interaction. Objective: To investigate the percentages of CD8+ lymphocytes and their subsets in...
متن کاملDiscovering lymphocyte subsets
At a scientific meeting in 1968, Jacques Miller was accused of complicating immunology. He and others suggested that there was not one but two kinds of lymphocytes--one from the thymus and one from the bone marrow. In a pair of groundbreaking articles published in the Journal of Experimental Medicine in 1968, Miller and his student Graham Mitchell proved that two subsets of lymphocytes did exis...
متن کاملLymphocyte subsets and activation.
The biology of lymphocytes is regulated by a large and seemi& growing number of soluble and cell-associated species. A current list includes: interleukins IL l-7, interferons, antigen and perhaps CD4 and cytokines derived from non-lymphoid tissues such as neuropepride, steroid and admnergic hormones. The quality and quantity of regulators present in the B cell milieu during an immunologic insul...
متن کاملHaemophilia and T lymphocyte subsets.
Number of circulating lymphocytes and T cell subsets were assessed in 13 boys with severe haemophilia and 12 age matched controls. There was no significant difference between the two groups. This conflicts with previous findings in adults where lymphopenia and changes in T cell subpopulations have been found frequently.
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Gut
سال: 2002
ISSN: 0017-5749
DOI: 10.1136/gut.50.2.150